Insulin derivatives having an extremely delayed time-action profile

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8633156
APP PUB NO 20110173722A1
SERIAL NO

12820727

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Abstract

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The invention relates to novel insulin analogs having a basal time-action profile, which are characterized by the addition and/or substitution of negatively and positively charged amino acid residues and by an amidation of the C-terminal carboxy group of the B chain and histidine in position 8 of the insulin A chain. The invention also relates to the production and use thereof.

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Patent Owner(s)

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SANOFI-AVENTIS DEUTSCHLAND GMBH65929 FRANKFURT AM MAIN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Habermann, Paul Frankfurt am Main, DE 46 702
Kurrle, Roland Frankfurt am Main, DE 9 243
Muller, Gunter Frankfurt am Main, DE 58 580
Seipke, Gerhard Frankfurt am Main, DE 16 346
Sommerfeld, Mark Frankfurt am Main, DE 21 153
Tennagels, Norbert Frankfurt am Main, DE 34 236
Tschank, Georg Frankfurt am Main, DE 38 739
Werner, Ulrich Frankfurt am Main, DE 45 471

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