Tubular nanostructure targeted to cell membrane

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United States of America Patent

SERIAL NO

12283907

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Abstract

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Devices, compositions, and methods are described which provide a tubular nanostructure or a composite tubular nanostructure targeted to a lipid bilayer membrane. The tubular nanostructure includes a hydrophobic surface region flanked by two hydrophilic surface regions. The tubular nanostructure is configured to interact with a lipid bilayer membrane and form a pore in the lipid bilayer membrane. The tubular nanostructure may be targeted by including at least one ligand configured to bind to one or more cognates on the lipid bilayer membrane of a target cell.

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Patent Owner(s)

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SEARETE LLC1756 - 114TH AVE S E # 110 BELLEVUE WA 98004

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bangera, Mahalaxmi Gita Renton, US 112 1971
Harlow, Ed Boston, US 49 577
Hyde, Roderick A Redmond, US 2911 61857
Ishikawa, Muriel Y Livermore, US 1367 34670
Jung, Edward KY Bellevue, US 1750 25284
Leuthardt, Eric C St. Louis, US 1186 32837
Myhrvold, Nathan P Medina, US 1337 34637
Rivet, Dennis J Portsmouth, US 394 16961
Sweeney, Elizabeth A Seattle, US 659 12786
Tegreene, Clarence T Bellevue, US 1905 49070
Wood, Victoria YH Livermore, US 835 16438
Wood,, JR Lowell L Bellevue, US 2836 53047

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