COMPOSITIONS AND METHODS FOR TREATING AND DIAGNOSING CANCER

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United States of America Patent

APP PUB NO 20110183866A1
SERIAL NO

13077380

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to compositions and methods for treating, characterizing, and diagnosing cancer. In particular, the present invention provides gene expression profiles and signatures associated with solid tumor stem cells, as well as novel stem cell cancer markers useful for the diagnosis, characterization, prognosis and treatment of solid tumor stem cells. More particularly, the present invention identifies two profiles of cancer stem cells useful for the diagnosis, characterization, and treatment of cancer and cancer metastases. The invention also provides a variety of reagents such as stem cell gene signatures for use in the diagnosis and management of cancer.

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Patent Owner(s)

Patent OwnerAddress
ONCOMED PHARMACEUTICALS INC800 CHESAPEAKE DRIVE REDWOOD CITY CA 94063-4748

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Clarke, Michael F Palo Alto, US 65 2958
Gurney, Austin L San Francisco, US 2150 9982
Lewicki, John A Los Gatos, US 45 1643
Wang, Xinhao Fremont, US 25 456

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