NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO

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United States of America Patent

APP PUB NO 20110200579A1
SERIAL NO

12375668

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Abstract

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The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO57290 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as cardiovascular, endothelial or angiogenic disorders; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; or developmental abnormalities.

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Patent Owner(s)

Patent OwnerAddress
GENENTECH INC1 DNA WAY SOUTH SAN FRANCISCO CA 94080
LEXICON PHARMACEUTICALS INC2445 TECHNOLOGY FOREST BLVD 11TH FLOOR THE WOODLANDS TX 77381

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cunningham, Jaime-Jo Austin, US 4 26
Vogel, Peter The Woodlands, US 82 1675

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