Oligonucleotide detection method

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United States of America Patent

PATENT NO 10711298
APP PUB NO 20110201006A1
SERIAL NO

13124411

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Abstract

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The invention relates to a method for the detection of oligonucleotides using anion exchange high performance liquid chromatography. Fluorescently labelled peptide nucleic acid oligomers, complementary to the oligonucleotide are hybridized to the oligonucleotides. Anion exchange high performance liquid chromatography is then performed and the hybridized moieties detected and quantitated. The invention also relates to a method for the simultaneous detection of both strands of an oligonucleotide in parallel from one sample, and a kit for use in qualitative and quantitative detection of one or two strands of an oligonucleotide.

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Patent Owner(s)

Patent OwnerAddress
AXOLABS GMBHFRITZ-HORNSCHUCH-STRASSE 9 KULMBACH D-95326

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Roehl, Ingo Memmelsdorf, DE 24 862
Schuster, Markus Bayreuth, DE 25 84
Seiffert, Stephan Kulmbach, CH 2 3

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