DIAGNOSTIC TEST FOR MUTATIONS IN CODONS 12-13 OF HUMAN K-RAS
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United States of America Patent
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Issued Date -
Aug 25, 2011
app pub date -
Dec 18, 2009
filing date -
Dec 19, 2008
priority date (Note) -
Abandoned
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Abstract
The invention is directed to compositions, methods and kits for diagnosing cancers and tumors correlated with mutations in codons 12 and 13 of human K-RAS using primers that amplify target sequences. The amplified target sequences are then analyzed by any number of mass spectrometric techniques, which data are queried against a database of base composition signatures of K-RAS mutations in codons 12 and 13.
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