METHOD TO INHIBIT RIBONUCLEASE DICER, RIBONUCLEASE DICER INHIBITOR, AND USE OF RNA APTAMERS AS RIBONUCLEASE DICER INHIBITORS
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United States of America Patent
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Issued Date -
Aug 25, 2011
app pub date -
Feb 9, 2009
filing date -
Feb 14, 2008
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Abandoned
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Abstract
The subject of the present invention is a method to inhibit ribonuclease Dicer, ribonuclease Dicer inhibitor, and use of RNA aptamers to inhibit ribonuclease Dicer. More specifically, this solution relates to using RNA aptamers as ribonuclease Dicer inhibitors that acts upon the competition basis (aptamers as competence inhibitors), use of RNA aptamers as allosteric ribonuclease Dicer inhibitors, and use of RNA aptamers as selective inhibitors of emergence of the selected miRNAs.
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