SN-38 COMPOSITIONS
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United States of America Patent
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Issued Date -
Aug 25, 2011
app pub date -
Feb 22, 2011
filing date -
Feb 23, 2010
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
In one aspect, the present invention is directed to a stable aqueous composition including (a) SN-38; (b) a sulfoalkyl derivative of a cyclodextrin; and (c) water; in which the concentration of SN-38 in the composition is at least about 0.13 mg/g of the composition. In another aspect, this invention is directed to a process for making the composition which process comprises mixing SN-38 and a sulfoalkyl derivative of a cyclodextrin in an aqueous medium wherein the water content of the mixture is less than about 60% by weight.
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