MAGNETIC HEATING FOR DRUG DELIVERY AND OTHER APPLICATIONS

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20110212163A1
SERIAL NO

13055195

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention generally relates to systems and methods for releasing a compound from an article using an external trigger, for example, magnetic fields. One aspect of the invention is generally directed to an article containing a magnetically-susceptible material. Exposure of the magnetically-susceptible material to a magnetic field, such as an oscillating magnetic field, may cause the magnetically-susceptible material to increase in temperature. This increase in temperature may be used, in some embodiments, to cause the release of a drug or other releasable material from the article. For instance, the drug may be contained in a heat-sensitive material in thermal communication with the magnetically-susceptible material, or the drug may be contained within an enclosure that is isolated, at least in part, by a heat-sensitive material in thermal communication with the magnetically-susceptible material. Other aspects of the invention are directed to systems and methods of making or using such articles, e.g., by implanting the article within a subject, methods of treatment involving such articles, kits including such articles, or the like.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139
CHILDREN'S MEDICAL CENTER CORPORATION55 SHATTUCK STREET BOSTON MA 02115
THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL55 FRUIT STREET BOSTON MA 02114

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hoare, Todd R Ontario, CA 5 112
Khushrushahi, Shahriar R Cambridge, US 2 25
Kim, Grace Y Cambridge, US 5 88
Kohane, Daniel S Newton, US 61 761
Langer, Robert S Newton, US 624 35600
Shapiro, Mikhail G Boston, US 24 477
Yeo, Yoon Cambridge, US 23 354

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