ORALLY RAPIDLY DISINTEGRATING TABLET AND PROCESS FOR PRODUCING SAME
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United States of America Patent
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Issued Date -
Sep 22, 2011
app pub date -
Nov 25, 2009
filing date -
Nov 25, 2008
priority date (Note) -
Published
status (Latency Note)
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Abstract
Disclosed is an orally rapidly disintegrating tablet characterized in that the tablet can be produced in a conventional tablet manufacturing facility and has a satisfactory level of hardness for practical applications, and the change in properties of the tablet (i.e., decreased in hardness of the tablet, and delay of the disintegration time of the tablet in the oral cavity) are rarely caused by factors such as humidity. The orally rapidly disintegrating tablet has hardness of 40N or more, can be disintegrated in the oral cavity within 60 seconds, and is produced by compressing of a mixture of (a) an active ingredient, (b) an excipient having good water wettability, (c) a water-insoluble polymer that is well compactible and does not substantially cause a decrease in the water wettability of the excipient and (d) a disintegrating agent.
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