Pegylated Opioids with Low Potential for Abuse
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United States of America Patent
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Issued Date -
Sep 29, 2011
app pub date -
Sep 16, 2009
filing date -
Sep 16, 2008
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Abstract
The invention provides opioid agonists covalently bound to a water-soluble oligomer having reduced potential for substance abuse and uses thereof. The compounds of the invention possess altered pharmacokinetic profiles relative to the opioid agonists alone, but are not subject to the risk of physical tampering that allows for the recovery and abuse of the opioid agonist associated with certain alternative delivery formulations.
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