SUBSTRATES FOR DRUG DELIVERY DEVICE AND METHODS OF PREPARING AND USE

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United States of America Patent

APP PUB NO 20110240014A1
SERIAL NO

13078668

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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An assembly and method for producing a condensation aerosol are disclosed. The assembly includes a heat-conductive metal substrate with an oxidation resistant exterior surface and a drug composition film on the exterior surface and is for use in an aerosol device. The thickness of the film and the surface of the substrate is such that the aerosol formed by vaporizing and condensing the drug composition the aerosol contain 10% by weight or less drug-degradation products and at least 50% of the total amount of the drug composition in the film. The methods for treating the exterior surface include heat and chemical treatment and formation of a protective overcoat.

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Patent Owner(s)

Patent OwnerAddress
ALEXZA PHARMACEUTICALS INC2091 STIERLIN CT MOUNTAIN VIEW CA 94043

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bennett, Bryson Mountain View, US 11 320
Hale, Ron L Woodside, US 72 5378
Lu, Amy Los Altos, US 10 683
Myers, Daniel J Mountain View, US 52 3133
Rabinowitz, Joshua D Princeton, US 167 12353
Sharma, Krishnamohan Santa Clara, US 29 940

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