PEPTIDE AGONISTS OF GLP-1 ACTIVITY
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United States of America Patent
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Issued Date -
Oct 6, 2011
app pub date -
Apr 29, 2010
filing date -
Jul 12, 1999
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Abandoned
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Abstract
Novel peptide agonists of GLP-1 activity useful for lowering blood glucose levels. The novel peptides comprise variants of the GLP-1 or the exendin-4 polypeptide sequence and are pharmacologically active and stable. These peptides are useful in the treatment of diseases that benefit from regulation of excess levels of blood glucose and/or regulation of gastric emptying, such as diabetes and eating disorders.
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