METHODS AND COMPOSITIONS FOR JOINT HEALING AND REPAIR
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United States of America Patent
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Issued Date -
Oct 6, 2011
app pub date -
Mar 7, 2011
filing date -
Mar 5, 2010
priority date (Note) -
Abandoned
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Abstract
The invention in some aspects provides implantable articles comprising in vitro-prepared tissues for joint repair. Devices and methods for introducing implantable articles into a subject are also provided. In some aspects of the invention devices and systems for minimally invasive surgery are provided. In some aspects, methods are provided for regenerating a bone-tendon interface in a subject by implanting an in vitro-prepared tissue between a detached tendon or detached ligament and a bone in a subject. In other aspects, methods are provided for maintaining exogenous, viable fibroblasts between a detached tendon and a bone in a subject. In other aspects, methods are provided for delivering exogenous cytokines and/or growth factors to a damaged bone-tendon interface.
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