Active Particles for Bio-Analytical Applications and Methods for Preparation Thereof

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United States of America Patent

APP PUB NO 20110262356A1
SERIAL NO

13056700

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Abstract

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Luminescent and/or electroactive nanoparticles suitable for MRI (Magnetic Resonance Imaging) and/or PET (Positron Emission Tomography) are prepared by mixing luminescent or electroactive compounds and ethyl oxide/propyl oxide block-copolymers in an organic solvent, which is thereafter evaporated in order to obtain a residue; and by hydrolyzing-condensating tetraalkoxysilanes in an aqueous solution in the presence of the residue; the obtained nanoparticles show no or a negligible release of the luminescent or electroactive compounds and are useful for bio-analytic and bio-medic applications.

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Patent Owner(s)

Patent OwnerAddress
ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNAVIA ZAMBONI 33 BOLOGNA (BO) 40126
CYANAGEN S R L40138 BOLOGNA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bonacchi, Sara Pistoia, IT 4 6
Ciana, Leopoldo Della Bologna, IT 13 386
Fabbroni, Serena Medicina, IT 5 5
Grilli, Stafano Medicina, IT 1 4
Juris, Ricarrdo Bologna, IT 1 4
Marzocchi, Ettore Bologna, IT 1 4
Montalti, Marco Calderara Di Reno, IT 4 6
Prodi, Luca Bologna, IT 7 6
Rampazzo, Enrico Bologna, IT 5 6
Zaccheroni, Nelsi Bologna, IT 5 6

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