EXPRESSION ANALYSIS OF CORONARY ARTERY ATHEROSCLEROSIS
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United States of America Patent
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Issued Date -
Nov 24, 2011
app pub date -
Oct 14, 2009
filing date -
Oct 14, 2008
priority date (Note) -
Abandoned
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Abstract
This invention relates, e.g., to a method for screening a subject for the presence of coronary atherosclerosis, said method comprising measuring the expression level of at least 5 of the genes of Table 2 in a biological sample obtained from said subject, wherein an elevated level of expression of said 5 genes compared to a control level measured in a population of normal subjects is indicative of an increased probability of the subject having significant subclinical coronary atherosclerosis. Methods for deciding on a treatment modality, based on a diagnostic procedure of the invention, are also described, as are kits for carrying out a method of the invention.
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