US Patent Application No: 2011/0294,149

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Alzheimer's Disease Secretase, APP Substrates Therefor, and Uses Therefor

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Abstract

The present invention provides the enzyme and enzymatic procedures for cleaving the β secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell isolates and assays. The invention further provides a modified APP protein and associated nucleic acids, peptides, vectors, cells, and cell isolates, and assays that are particularly useful for identifying candidate therapeutics for treatment or prevention of Alzheimer's disease.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ELAN PHARMACEUTICALS, INC.SOUTH SAN FRANCISCO, CA343

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bienkowski, Michael J Portage, MI 28 275
Gurney, Mark E Grand Rapids, MI 82 311
Heinrikson, Robert L Plainwell, MI 37 272
Parodi, Luis A Stockholm, SE 36 290
Yan, Riqiang Kalamazoo, MI 39 288

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