BIOMOLECULE COMPLEXES AS CONTRAST AGENTS IN POSITRON EMISSION TOMOGRAPHY (PET) BASED METHODS FOR THE ASSESSMENT OF ORGAN FUNCTION
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United States of America Patent
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Issued Date -
Dec 8, 2011
app pub date -
Dec 10, 2009
filing date -
Dec 10, 2008
priority date (Note) -
Abandoned
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Abstract
The present invention relates to complexes comprising one or more markers and one or more biomolecules for use as a contrast agent in positron emission tomography based imaging. The complexes according to the present invention preferably accumulate in a target compartment, such as the kidney. The present invention further relates to methods for generating the complexes and methods for using the complexes such as for evaluation of different aspects of kidney functionality e.g. for calculation of total and/or regional glomerular filtration rate in the kidney without the need for sampling blood or urine.
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