US Patent Application No: 2011/0300,162

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DRUG CONJUGATE COMPOSITION

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Abstract

The invention provides a liquid composition and a lyophilized composition comprising a therapeutically effective amount of a conjugate comprising an antibody chemically coupled to a maytansinoid. The invention further provides a method for killing a cell in a human comprising administering to the human either of the compositions such that the antibody binds to the surface of the cell and the cytotoxicity of the maytansinoid is activated, whereby the cell is killed.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
IMMUNOGEN, INC.WALTHAM, MA89

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Amphlett, Godfrey Cambridge, MA 13 25
Chih, Hung-Wei Cambridge, MA 8 11
Fleming, Michael Londonderry, NH 24 101
Zhang, Wei Beijing, CN 617 1688

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
IMMUNOGEN, INC. (1)
8,435,528 Cytotoxic agents comprising new maytansinoids 0 2007