METHOD TO ENHANCE OSTEOBLAST FUNCTIONALITY AND MEASURE ELECTROCHEMICAL PROPERTIES FOR A MEDICAL IMPLANT

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United States of America Patent

APP PUB NO 20110301716A1
SERIAL NO

12668706

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method to enhance osteoblast functionality of a medical implant. The method may include obtaining the medical implant and treating a surface of the medical implant to modify the surface characteristics causing increase functionality of adjacent positioned osteoblasts. A method of increasing cellular activity of a medical implant is also disclosed. A medical device having enhanced cytocompatibility capabilities includes a metallic substrate with an outer surface. Attached to the outer surface is a composition of nanosized structures. A biosensor for use with a medical device, includes an electrode that is attached to an outer surface of the medical device. The biosensor measures electrochemical changes adjacent to the medical implant. Further, a method of manufacturing a medical implant with a biosensor for use in vivo and a method of integrating a biosensor with a medical implant for use in monitoring conductivity and electrochemical changes adjacent to the medical implant are disclosed.

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Patent Owner(s)

Patent OwnerAddress
BROWN UNIVERSITYBOX 1949 PROVIDENCE RI 02912

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sheldon, Brian Providence, US 3 66
Sirivisoot, Sirinrath Winston-Salem, US 1 66
Webster, Thomas Providence, US 23 257
Xiao, Xingcheng Providence, US 68 2112
Yao, Chang Providence, US 10 147

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