US Patent Application No: 2011/0302,665

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NON-HUMAN MAMMALS WITH T OR B CELLS HAVING PREDEFINED SPECIFICITY

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Abstract

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The present invention provides non-human mammals, e.g., mice, generated from a T cell or B cell with a predefined specificity or isolated from an organism suffering from a condition of interest. In some embodiments the non-human mammals are not genetically modified. Also provided are methods of using the non-human animals.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCHCAMBRIDGE, MA196

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Frickel, Eva-Maria - 1 0
Grotenbreg, Gijsbert M - 1 0
Jaenisch, Rudolf Brookline, MA 32 38
Kirak, Oktay - 2 0
Ploegh, Hidde - 2 0

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