NON-HUMAN MAMMALS WITH T OR B CELLS HAVING PREDEFINED SPECIFICITY

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United States of America Patent

APP PUB NO 20110302665A1
SERIAL NO

13002334

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Abstract

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The present invention provides non-human mammals, e.g., mice, generated from a T cell or B cell with a predefined specificity or isolated from an organism suffering from a condition of interest. In some embodiments the non-human mammals are not genetically modified. Also provided are methods of using the non-human animals.

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Patent Owner(s)

Patent OwnerAddress
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH455 MAIN STREET CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Frickel, Eva-Maria London, GB 1 1
Grotenbreg, Gijsbert M Singapore, SG 1 1
Jaenisch, Rudolf Brookline, US 56 829
Kirak, Oktay Boston, US 2 120
Ploegh, Hidde Brookline, US 6 55

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