TARGETING TUMOR ASSOCIATED MACROPHAGES USING BISPHOSPHONATE-LOADED PARTICLES

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United States of America Patent

APP PUB NO 20110311616A1
SERIAL NO

13162419

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided herein are compositions including particles that comprise a bisphosphonate compound and a tumor specific targeting peptide or peptidomimetic. Also provided herein are methods of reducing tumor associated macrophages and methods of treating cancer with said compositions.

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Patent Owner(s)

Patent OwnerAddress
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE10901 NORTH TORREY PINES ROAD LA JOLLA CA 92037

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sharma, Gaurav San Diego, US 155 2048
Smith, Jeff San Diego, US 94 2507

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