PHARMACEUTICAL COMPOSITION AND SYSTEM FOR PERMEABILIZING FETAL MEMBRANES
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United States of America Patent
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Issued Date -
Dec 29, 2011
app pub date -
Nov 25, 2009
filing date -
Nov 25, 2008
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
Provided is a pharmaceutical composition for permeabilizing fetal membranes including an active ingredient having a log K in the range of 2 to 4, where K is the octanol/water partition coefficient. The active ingredient may be, for example, bupivacaine, sodium lauryl sulfate or oleic acid. Further provided is a system for transfetal membrane transport. The system includes a probe unit adapted for insertion into a female reproductive tract and releasing a substance onto fetal membranes that permeabilizes the membranes. The system is also configured to apply ultrasound radiation to the fetal membranes to further increase the membrane permeability.
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Family
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