Vaccines based on targeting antigen to DCIR expressed on antigen-presenting cells

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United States of America Patent

PATENT NO 8449888
APP PUB NO 20120004643A1
SERIAL NO

13234914

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Abstract

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The present invention includes compositions and methods for increasing the effectiveness of antigen presentation using a DCIR-specific antibody or fragment thereof to which an antigen is attached that forms an antibody-antigen complex, wherein the antigen is processed and presented by a dendritic cell that has been contacted with the antibody-antigen complex.

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Patent Owner(s)

Patent OwnerAddress
BAYLOR RESEARCH INSTITUTE3434 LIVE OAK STREET DALLAS TX 75204

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Banchereau, Jacques F Montclair, US 94 1559
Flamar, Anne-Laure Dallas, US 23 836
Klechevsky, Eynav Haifa, IL 18 417
Zurawski, Gerard Midlothian, US 87 1622
Zurawski, Sandra Midlothian, US 52 755

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