METHOD OF TREATING CANCER

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United States of America Patent

APP PUB NO 20120022026A1
SERIAL NO

13144079

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a method of treating or preventing hyperproliferative disease in a body tissue of a subject, comprising the steps of administering to a subject in need thereof a therapeutically effective amount of an agent that induces double strand breaks in the DNA of the hyperproliferative cells of said body tissue; and subjecting the hyperproliferative cells of said body tissue prior to, simultaneously with or subsequent to step a) to hyperthermia to thereby induce in said cells the degradation, inhibition and/or inactivation of BRCA2.

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Patent Owner(s)

Patent OwnerAddress
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM1105 AZ AMSTERDAM
ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAMDR MOLEWATERPLEIN 50 ROTTERDAM 3015 GE

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aten, Jacob A Amsterdam, NL 1 8
Essers, Jeroen Rotterdam, NL 2 10
Kanaar, Roland Rotterdam, NL 3 11
Krawczyk, Przemyslaw Amsterdam, NL 1 8

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