MATRIX-TYPE SUSTAINED RELEASE PREPARATION CONTAINING BASIC ADDITIVE
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United States of America Patent
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Issued Date -
Feb 2, 2012
app pub date -
Mar 26, 2010
filing date -
Mar 27, 2009
priority date (Note) -
Abandoned
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Abstract
Disclosed is a matrix-type sustained release preparation containing a basic drug unstable against an acid as an active pharmaceutical ingredient, wherein the decomposition of the basic drug unstable against the acid can be prevented and therefore the pH-dependent release can be reduced. A hardly water-soluble basic normal salt is added to a matrix-type sustained release preparation containing a basic drug that is unstable against an acid.
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