IRAK KINASE FAMILY AS NOVEL TARGET AND BIOMARKER FOR ALZHEIMER
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United States of America Patent
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Issued Date -
Feb 9, 2012
app pub date -
Apr 26, 2010
filing date -
Apr 24, 2009
priority date (Note) -
Abandoned
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Abstract
The present invention relates to methods and devices for the diagnosis or drug response prediction of neurological disorders by measuring kinase activity and studying the phosphorylation levels and profiles in samples of said patients. Furthermore the present invention relates to methods of identifying drug compounds relevant to neurological disorders by measuring kinase activity and studying phosphorylation levels. Also, the present invention relates to the use of inhibitors of the IRAK protein kinase family or a pharmaceutical composition thereof in the treatment of neurological disorders such as Alzheimer's disease.
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