Methods for forming dyed microspheres and populations of dyed microspheres
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United States of America Patent
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Jan 29, 2013
Grant Date -
Feb 9, 2012
app pub date -
Sep 27, 2011
filing date -
Oct 12, 2004
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Abstract
Various methods for forming dyed microspheres are provided. One method includes activating a chemical structure coupled to a dye using heat or light to form a reaction intermediate in the presence of a microsphere. The reaction intermediate covalently attaches to a polymer of the microsphere thereby coupling the dye to the polymer and forming the dyed microsphere. Additional methods are provided for forming a dyed microsphere coupled to a molecule. These methods include dyeing the microspheres as described above in addition to synthesizing the molecule on an outer surface of the dyed microspheres. A population of dyed microspheres is also provided. Each of the dyed microspheres of the population includes a dye attached to a polymer of each of the dyed microspheres by a chemical structure. A coefficient of variation in dye characteristics of the population of dyed microspheres attributable to the dye is less than about 10%.
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- 15 United States
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Patent Owner(s)
- LUMINEX CORPORATION
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Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Hoffacker, Kurt D | Austin, US | 10 | 156 |
Lugade, Ananda G | Austin, US | 18 | 398 |
Terpetschnig, Ewald | Urbana, US | 9 | 374 |
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