9-(piperazinylalkyl) carbazoles as Bax-modulators

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United States of America Patent

PATENT NO 8410110
APP PUB NO 20120040933A1
SERIAL NO

13225760

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Abstract

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Piperazine compounds for use as pharmaceutically active compounds and in pharmaceutical formulations that are useful for the treatment of disorders associated with apoptosis, including neurodegenerative disorders, diseases associated with polyglutamine tracts, epilepsy, ischemia, infertility, cardiovascular disorders, renal hypoxia, hepatitis and AIDS, where the piperazine compounds are represented by formula (I) and the terms R0, R1, R2, R3, k, l, m, n, and X are defined herein:

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Patent Owner(s)

  • MERCK SERONO SA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Antonsson, Bruno Billiat, FR 5 75
Bombrun, Agnes Monnetier-Mornex, FR 44 424
Church, Dennis Commugny, CH 25 262
Gerber, Patrick Villars-Sous-Yens, CH 17 64
Halazy, Serge Vetraz-Monthoux, FR 31 363
Martinou, Jean-Claude Versonnex, FR 5 38

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