NOVEL DISSOLUTION TESTING SYSTEM AND APPARATUS WITH OFF-CENTER IMPELLER
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United States of America Patent
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Issued Date -
Feb 23, 2012
app pub date -
Apr 13, 2011
filing date -
Apr 13, 2010
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
, which were well within the accepted ranges and did not change appreciably with the tablet location. By contrast, the corresponding dissolution tests for current systems failed these similarity tests. In addition, the flow fields near the vessel bottom were obtained via CFD simulation and were found to be significantly more uniform in e present invention than in the current standard apparatus. The present invention has the potential of becoming a valid alternative to the standard USP dissolution testing apparatuses used for dissolution testing.
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