Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
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United States of America Patent
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Issued Date -
Feb 23, 2012
app pub date -
Feb 9, 2010
filing date -
Feb 10, 2009
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Abandoned
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Abstract
and T are as defined in the claims, that bind to thyroid receptors in the liver. Activation of these receptors results in modulation of gene expression of genes regulated by thyroid hormones. The compounds can be used to treat diseases and disorders including metabolic diseases such as obesity, NASH, hypercholesterolemia and hyperlipidemia, as well as associated conditions such as atherosclerosis, coronary heart disease, impaired glucose tolerance, metabolic syndrome X and diabetes.
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