OPTIMIZED ANTIBODIES THAT TARGET CD19
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United States of America Patent
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app pub date -
Aug 30, 2011
filing date -
Aug 14, 2006
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Abandoned
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Abstract
The present invention describes antibodies that target CD19, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an FcγR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the antibodies of the invention.
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