PARKIN SUBSTRATE AND ASSAY

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United States of America Patent

APP PUB NO 20120083003A1
SERIAL NO

13276175

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides in vitro, ex vivo, and in vivo assays for Parkin activity, in which Parkin-mediated ubiquitination of a Sept4 protein is measured. The assays may be used to screen for agents that modulate Parkin protein ligase activity.

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Patent Owner(s)

Patent OwnerAddress
ELAN PHARMA INTERNATIONAL LIMITEDTREASURY BUILDING LOWER GRAND CANAL STREET DUBLIN 2

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cutcliffe, Colleen Tsui Menlo Park, US 2 6
Johnston, Jennifer A Mill Valley, US 9 15

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