NANOCARRIER HAVING ENHANCED SKIN PERMEABILITY, CELLULAR UPTAKE AND TUMOUR DELIVERY PROPERTIES

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20120087859A1
SERIAL NO

13378330

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention relates to a biopolymer-modified nanocarrier in which chitosan is bound to a water-soluble biocompatible polymer that has been crosslinked via a photo-crosslinkable functional group; wherein the chitosan-modified nanocarrier has a diameter which changes in accordance with changes in temperature, has enhanced skin permeability or cellular uptake and selective delivery to cancer tissue as compared with a bare nanocarrier to which chitosan has not been bound, and exhibits characteristics that are advantageous in photothermal therapy. The chitosan-modified nanocarrier of the present invention exhibits highly superior efficacy as a transdermal carrier, since the skin permeability is enhanced to a significant level as compared with a bare nanocarrier that has no chitosan. The chitosan-modified nanocarrier of the present invention can be advantageous in the imaging and photothermal therapy of tumour cells and cancer cells, since the cellular uptake by tumour cells and cancer cells is substantially improved.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY123 CHEOMDANGWAGI-RO BUK-GU GWANGJU 61005

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Choi, Won II Gwangju, KR 3 3
Kim, Ja-Young Gwangju, KR 6 52
Kim, Young Ha Gwangju, KR 47 922
Lee, Jong Hyun Gwangju, KR 227 1466
Tae, Gi Yoong Gwangju, KR 3 12

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation