METHODS AND COMPOSITIONS FOR ANALYSIS OF REGULATORY SEQUENCES
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United States of America Patent
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Issued Date -
Apr 12, 2012
app pub date -
Dec 19, 2011
filing date -
Nov 15, 2002
priority date (Note) -
Abandoned
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Abstract
Methods for constructing arrays of regulatory sequences, and the arrays so obtained, are provided. Regulatory sequences for use on the arrays are isolated based on their accessibility in cellular chromatin. A number of methods for using the arrays are disclosed, including regulatory DNA profiling, epigenome profiling, toxicological profiling and identification of in vivo binding sites of DNA binding proteins in complex genomes.
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