METHOD FOR THE TREATMENT OF ACUTE MYELOID LEUKEMIA
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United States of America Patent
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Issued Date -
Apr 12, 2012
app pub date -
Apr 22, 2010
filing date -
Apr 22, 2009
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Abandoned
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Abstract
The invention is in the field of molecular medicine and provides methods for the treatment of acute myeloid leukemia. These methods are based on the observation that microRNA-9 and microRNA-9* are involved in the pathogenesis of the disease in that the overexpression of microRNA-9/9* block myeloid differentiation in vitro. More in particular, microRNA-9/9* were found to play a role in leukemic transformation in acute myeloid leukemia.
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