GAS-FILLED MICROVESICLES WITH TARGETING LIGAND OR THERAPEUTIC AGENT
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United States of America Patent
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app pub date -
Dec 19, 2007
filing date -
Dec 19, 2006
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Abandoned
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Abstract
Gas-filled microvesicles comprising a boundary envelope containing a gas, wherein said microvesicles comprise: —a first component, bound to said envelope, having binding affinity for an Fc-region of an antibody; and—a second component comprising a Fc-region of an antibody, bound to said first component through said Fc-region, said second component comprising a targeting ligand or a therapeutic agent. Aqueous suspensions of said microvesicles are particularly useful in contrast enhanced ultrasound imaging.
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