Manganese-oxo clusters as contrast agents for magnetic resonance imaging

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United States of America Patent

PATENT NO 9555134
APP PUB NO 20120134932A1
SERIAL NO

13125244

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Abstract

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Nanoparticles for use as magnetic resonance imaging contrast agents are described. The nanoparticles are made up of a polymeric support and a manganese-oxo or manganses-iron-oxo cluster having magnetic properties suitable of a contrast agent. The manganese-oxo clusters may be Mn-12 clusters, which have known characteristics of a single molecule magnet. The polymer support may form a core particle which is coated by the clusters, or the clusters may be dispersed within the polymeric agent.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
GEORGETOWN UNIVERSITYWASHINGTON, DC199

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Albanese, Christopher Pelham Manor, US 3 4
Fricke, Stanley New Market, US 1 0
Mertzman, Julie Washington, US 1 0
Stoll, Sarah Washington, US 1 0
Van, Keuren Edward Herndon, US 3 0

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
* 2005/0265,923 Embolus therapy using insoluble microparticles or vesicles containing contrast agents 10 2005
 
SERADYN, INC. (1)
* 5648124 Process for preparing magnetically responsive microparticles 51 1995
 
MALLINCKRODT MEDICAL, INC. (1)
5330742 Methods and compositions for magnetic resonance imaging 18 1992
* Cited By Examiner

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