Manganese-oxo clusters as contrast agents for magnetic resonance imaging
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United States of America Patent
Stats
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Jan 31, 2017
Grant Date -
May 31, 2012
app pub date -
Oct 21, 2009
filing date -
Oct 21, 2008
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
Nanoparticles for use as magnetic resonance imaging contrast agents are described. The nanoparticles are made up of a polymeric support and a manganese-oxo or manganses-iron-oxo cluster having magnetic properties suitable of a contrast agent. The manganese-oxo clusters may be Mn-12 clusters, which have known characteristics of a single molecule magnet. The polymer support may form a core particle which is coated by the clusters, or the clusters may be dispersed within the polymeric agent.
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Cited Art Landscape
| Patent Info | (Count) | # Cites | Year |
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| * 2005/0265,923 Embolus therapy using insoluble microparticles or vesicles containing contrast agents | 12 | 2005 | |
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| * 5648124 Process for preparing magnetically responsive microparticles | 53 | 1995 | |
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| 5330742 Methods and compositions for magnetic resonance imaging | 18 | 1992 | |
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