IMMUNOGENIC COMPOSITION COMPRISING ANTIGENIC S. AUREUS PROTEINS
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United States of America Patent
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Issued Date -
Jun 7, 2012
app pub date -
Aug 3, 2010
filing date -
Aug 5, 2009
priority date (Note) -
Abandoned
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Abstract
The present application relates to an immunogenic composition comprising a fragment of a staphylococcal Isd protein such as IsdA, IsdB, IsdC or IsdH which comprises a NEAT domain. Fusion proteins comprising a NEAT domain of a first staphylococcal Isd protein and a NEAT domain from a second Isd protein are also disclosed as well as fusion proteins comprising a NEAT domain of a staphylococcal Isd protein involved in an iron/heme uptake system and a ligand binding domain of a staphylococcal extracellular component binding protein, for example ClfA, ClfB, SdrC, SdrD or SdrE.
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