ANTIVIRULENCE COMPOUNDS INHIBITING BACTERIAL MONO-ADP-RIBOSYLTRANSFERASE TOXINS
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United States of America Patent
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Issued Date -
Jun 7, 2012
app pub date -
Dec 2, 2011
filing date -
Dec 2, 2010
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Abandoned
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Abstract
Compounds that inhibit bacterial virulence factors from the mono-ADP-ribosyltransferase (mART) family of toxins have been identified that are not toxic to cells or the producing bacterial pathogen. These compounds have great potential as antivirulence agents for treating many bacterial infections and disease states.
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