SIMULTANEOUS DETERMINATION OF ANEUPLOIDY AND FETAL FRACTION
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United States of America Patent
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Issued Date -
Jun 28, 2012
app pub date -
Feb 2, 2012
filing date -
Jan 19, 2010
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Abstract
The invention provides compositions and methods for simultaneously determining the presence or absence of fetal aneuploidy and the relative amount of fetal nucleic acids in a sample obtained form a pregnant female. The method encompasses the use of sequencing technologies and exploits the occurrence of polymorphisms to provide a streamlined noninvasive process applicable to the practice of prenatal diagnostics.
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