IDENTIFICATION OF REGULATORY T CELLS VIA THE GLOBAL GENE REGULATOR SATB1
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United States of America Patent
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Issued Date -
Jul 5, 2012
app pub date -
Apr 6, 2010
filing date -
Apr 2, 2009
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Abandoned
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Abstract
A method for the identification of regulatory T cells based on the diminished abundance or even absence of the global gene regulator SATB1 in such regulatory T cells. In particular, the invention relates to a method utilizing ligands that specifically bind to SATB1 for identifying regulatory T cells which are cells showing a reduced binding to said ligand. Such method is suitable for quality determination of a regulatory T cell population. A kit or diagnostic composition for such method is also disclosed.
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