Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometry

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United States of America Patent

PATENT NO 8481478
APP PUB NO 20120190560A1
SERIAL NO

13410183

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Abstract

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Disclosed here is a method for measuring the kinetics (i.e., the molecular flux rates—synthesis and breakdown or removal rates) of a plurality of proteins or organic metabolites in living systems. The methods may be accomplished in a high-throughput, large-scale automated manner, by using existing mass spectrometric profiling techniques and art well known in the fields of static proteomics and static organeomics, without the need for additional biochemical preparative steps or analytic/instrumental devices.

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Patent Owner(s)

Patent OwnerAddress
REGENTS OF THE UNIVERSITY OF CALIFORNIA THE1111 FRANKLIN STREET 12TH FLOOR A CALIFORNIA CORPORATION OAKLAND CA USA 94607-5200

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hellerstein, Marc K Kensington, US 53 1124

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