Fusion Protein of an Anti-CD20 Antibody Fab Fragment and Lidamycin, a Method for Preparing the Same, and the Use Thereof

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United States of America Patent

APP PUB NO 20120195895A1
SERIAL NO

13387531

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Abstract

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The present invention relates to an anticancer drug, an energized fusion protein Anti-CD20(Fab)-LDM of lidamycin, a gene encoding the same; and further relates to a method for construction of the energized fusion protein in a genetic engineering manner and the use of the energized fusion protein. The applicant provides an anti-tumor drug with a good targeting ability by providing the energized fusion protein.

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Patent Owner(s)

Patent OwnerAddress
INSTITUTE OF HEMATOLOGY CHINESE ACADEMY OF MEDICAL SCIENCES & PEKING UNION MEDICAL COLLEGE288 NANJING ROAD TIANJIN 300020

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheng, Xin Tianjin, CN 94 452
Fang, Hong Beijing, CN 25 38
Gao, Yingdai Tianjin, CN 1 0
Jin, Lianfang Beijing, CN 1 0
Miao, Qingfang Beijing, CN 2 0
Shao, Rongguang Beijing, CN 2 0
Xiong, Dongsheng Tianjin, CN 3 11
Xu, Yuanfu Tianjin, CN 4 0
Yang, Chunzheng Tianjin, CN 3 2
Zhang, Shenghua Beijing, CN 9 154
Zhen, Yongsu Beijing, CN 2 0
Zhu, Zhenping Tianjin, CN 43 483

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