FOLATE RECEPTOR ALPHA AS A DIAGNOSTIC AND PROGNOSTIC MARKER FOR FOLATE RECEPTOR ALPHA-EXPRESSING CANCERS

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United States of America Patent

APP PUB NO 20120207771A1
SERIAL NO

13289892

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Abstract

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The present invention provides methods and kits for assessing whether a subject is afflicted with an FRα-expressing cancer, methods and kits for predicting the progression of ovarian cancer in a subject afflicted with an FRα-expressing cancer, methods and kits for assessing the level of risk that a subject will develop an FRα-expressing cancer, and methods of stratifying a subject with an FRα-expressing cancer into cancer therapy groups. The methods involve determining the level of folate receptor alpha (FRα) which is not bound to a cell in a sample derived from the subject and comparing this level with the level of FRα in a control sample.

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Patent Owner(s)

Patent OwnerAddress
MORPHOTEK INC210 WELSH POOL ROAD EXTON PA 19341

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chao, Qimin Havertown, US 8 106
Grasso, Luigi Bryn Mawr, US 100 824
O'Shannessy, Daniel J Schwenksville, US 7 126
Somers, Elizabeth Brooke Unionville, US 1 31
Wan, Shanhong Paoli, US 2 31

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