EXTRACELLULAR YALURONIDASE FROM STREPTOMYCES KOGANEIENSIS
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United States of America Patent
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Issued Date -
Mar 22, 2012
app pub date -
May 14, 2009
filing date -
May 14, 2009
priority date (Note) -
Abandoned
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Abstract
The invention relates to Streptomyces koganeiensis ATCC 31394 hyaluronidase having molecular weight of 21.6 kDalton, which has hyaluronidase activity and stability markedly higher than those of the hyaluronidase obtained from such microorganism to date. The invention further relates to a process for the isolation and purification of said hyaluronidase and its use for the preparation of pharmaceutical compositions or as an analytical reagent.
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