METHOD OF TARGETING SPECIFIC CELL POPULATIONS USING CELL-BINDING AGENT MAYTANSINOID CONJUGATES LINKED VIA A NON-CLEAVABLE LINKER, SAID CONJUGATES AND METHODS OF MAKING SAID CONJUGATES

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United States of America Patent

SERIAL NO

13469550

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Abstract

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The present invention discloses a method for targeting maytansinoids to a selected cell population, the method comprising contacting a cell population or tissue suspected of containing the selected cell population with a cell-binding agent maytansinoid conjugate, wherein one or more maytansinoids is covalently linked to the cell-binding agent via a non-cleavable linker and the cell-binding agent binds to cells of the selected cell population.

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Patent Owner(s)

Patent OwnerAddress
IMMUNOGEN INCWALTHAM MA 02451

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BLATTLER, Walter A Brookline, US 52 3527
CHARI, Ravi VJ Newton, US 94 914
STEEVES, Rita M Stoneham, US 7 249
WIDDISON, Wayne Somerville, US 3 24

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