Live attenuated rotavirus vaccine for oral administration
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United States of America Patent
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Sep 2, 2014
Grant Date -
Sep 20, 2012
app pub date -
Jun 1, 2012
filing date -
Feb 17, 2005
priority date (Note) -
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Abstract
The invention provides liquid rotavirus formulations that are suitable for oral administration to human infants. In particular the invention provides pharmaceutical compositions and vaccines, comprising a rotavirus antigen, a sugar and a carboxylate wherein said formulation has a pH of between pH 5.0 and pH 8.0 and comprises no phosphate or less than 5 mM phosphate. The invention also provides methods of preparing said rotavirus formulations and use thereof in the prevention or treatment of rotavirus associated diseases in humans.
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Family
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