METHODS AND KITS FOR IDENTIFYING HUMAN ADENOVIRUS SEROTYPES
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United States of America Patent
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Issued Date -
Oct 18, 2012
app pub date -
Dec 20, 2010
filing date -
Dec 23, 2009
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Abstract
Methods, kits, primers and oligonucleotide probes for conveniently and rapidly detecting and identifying four or more human adenovirus (HAdV) serotypes in a sample are provided. Following a nucleic acid amplification reaction with specific primers, serotype specific oligonucleotide probes are used not only to detect HAdV present in a sample but also to discriminate between the HAdV serotypes present in the sample, and in particular to discriminate between the clinically relevant serotypes HAdV-3, HAdV-4, HAdV-7, HAdV-14, and HAdV-21 and/or HAdV-I, HAdV-2, HAdV-5, and HAdV-6. The combination of these primers and oligonucleotide probes permit the rapid and convenient serotyping of HAdV.
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